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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC3
All Species:
44.24
Human Site:
S674
Identified Species:
69.52
UniProt:
Q9UQE7
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQE7
NP_005436.1
1217
141542
S674
G
Y
Y
D
T
R
K
S
R
L
E
L
Q
K
D
Chimpanzee
Pan troglodytes
XP_508031
1374
158072
S831
G
Y
Y
D
T
R
K
S
R
L
E
L
Q
K
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851818
1228
142683
S674
G
Y
Y
D
T
R
K
S
R
L
E
L
Q
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CW03
1217
141537
S674
G
Y
Y
D
T
R
K
S
R
L
E
L
Q
K
D
Rat
Rattus norvegicus
P97690
1191
138430
S674
G
Y
Y
D
T
R
K
S
R
L
E
L
Q
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512851
1238
143475
S695
G
Y
Y
D
T
R
K
S
R
L
E
L
Q
K
D
Chicken
Gallus gallus
Q90988
1189
134923
V671
S
G
G
A
S
S
H
V
T
P
I
L
S
K
L
Frog
Xenopus laevis
O93309
1209
140704
S674
G
Y
Y
D
T
R
K
S
R
L
E
L
Q
K
D
Zebra Danio
Brachydanio rerio
NP_999854
1216
141517
S674
G
Y
Y
D
T
R
K
S
R
L
E
L
Q
K
D
Tiger Blowfish
Takifugu rubipres
NP_001027798
1217
141541
S674
G
Y
Y
D
T
R
K
S
R
L
E
L
Q
K
D
Fruit Fly
Dros. melanogaster
NP_523374
1200
140018
S675
G
Y
F
N
T
S
R
S
R
L
E
M
Q
K
K
Honey Bee
Apis mellifera
XP_393700
1202
139436
S674
G
Y
F
N
T
L
R
S
R
L
E
I
Q
K
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202053
792
92535
E332
E
D
L
Q
R
E
E
E
Q
C
T
A
R
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SN90
1171
132296
G666
T
G
G
S
R
K
G
G
G
D
L
L
R
Q
L
Baker's Yeast
Sacchar. cerevisiae
P47037
1230
141318
R682
G
Y
L
D
Q
H
K
R
T
R
L
E
S
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
N.A.
99
N.A.
99.9
97.2
N.A.
97.5
23.3
95.8
95.1
94.9
53.4
55.4
N.A.
40.1
Protein Similarity:
100
88.5
N.A.
99
N.A.
100
97.4
N.A.
98
46.5
97.6
97.5
97.3
73.2
72.9
N.A.
53.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
13.3
100
100
100
60
60
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
20
100
100
100
86.6
86.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47
57.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
7
0
67
0
0
0
0
0
7
0
0
0
0
60
% D
% Glu:
7
0
0
0
0
7
7
7
0
0
74
7
0
0
0
% E
% Phe:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
80
14
14
0
0
0
7
7
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% I
% Lys:
0
0
0
0
0
7
67
0
0
0
0
0
0
80
14
% K
% Leu:
0
0
14
0
0
7
0
0
0
74
14
74
0
14
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
7
7
0
0
0
7
0
0
0
74
7
7
% Q
% Arg:
0
0
0
0
14
60
14
7
74
7
0
0
14
0
0
% R
% Ser:
7
0
0
7
7
14
0
74
0
0
0
0
14
0
0
% S
% Thr:
7
0
0
0
74
0
0
0
14
0
7
0
0
0
7
% T
% Val:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
80
60
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _